Vinyl Chloride Bones

Vinyl chloride is primarily used to make polyvinyl chloride to manufacture plastics.

Vinyl chloride bones.

Vinyl chloride is used primarily to make polyvinyl chloride pvc. Oncogenic response of rat skin lungs and bones to vinyl chloride. Vinyl chloride monomer. Viola pl bigotti a caputo a.

Repeated exposure can damage the skin scleroderma bones acro osteolysis and blood vessels in the hand raynaud s syndrome scleroderma is characterized by a hardening and tightening of patches of skin. Pvc is used to make a variety of plastic products including pipes wire and cable coatings and packaging materials. High levels of vinyl chloride in the air also lead to blanching of fingers numbness discomfort changes in the bones at the end of the fingers joint and muscle pain and scleroderma like skin changes such as thickening of the skin decreased elasticity and slight edema. Vinyl chloride is a manufactured substance that does not occur naturally.

These exposures have resulted in what has been called vinyl chloride disease a syndrome consisting of raynaud s phenomenon blanching numbness and discomfort of the fingers upon exposure to cold degeneration of the fingertip bones acroosteolysis joint and muscle pain and stiffness of the hands with skin changes. Vinyl chloride disease is a syndrome consisting of raynaud s phenomenon acroosteolysis dissolution of the bones of the terminal phalanges and sacroiliac joints and scleroderma like skin changes. J toxicol environ health. Wagoner jk infante pf apfeldorf rb.

It does not occur naturally and must be produced industrially for its commercial uses. What is vinyl chloride. A small percentage of individuals occupationally exposed to high levels of vinyl chloride in air have developed a set of symptoms termed vinyl chloride disease which is characterized by raynaud s phenomenon fingers blanch and numbness and discomfort are experienced upon exposure to the cold changes in the bones at the end of the fingers. Toxicity of vinyl chloride and polyvinyl chloride as seen through epidemiologic observations.

However it can be formed in the environment when other manufactured substances such as trichloroethylene trichloroethane and tetrachloroethylene are broken down by certain microorganisms. Vinyl chloride is a chlorinated hydrocarbon occurring as a colorless highly flammable gas with a mild sweet odor that may emit toxic fumes of carbon dioxide carbon monoxide hydrogen chloride and phosgene when heated to decomposition.