Vinyl Chloride Disease

Each peer reviewed profile identifies and reviews the key literature that describes a hazardous substance s toxicologic properties.

Vinyl chloride disease.

There is no treatment for this disease. Pyramidal syndromes in 52 cerebellar disturbances in 38. Other pertinent literature is also presented but is described in less detail than the key studies. Exposed to vinyl chloride for 1 to 25 yr mean 14 58 i e.

Devic s disease a demyelinative disease of the optic nerve the optic chiasma and the spinal cord characterized by a bilateral acute optic neuritis with a transverse inflammation of the spinal cord. 44 in combination with positive neurological findings i e. Vinyl chloride is a known human carcinogen that causes a rare cancer of the liver. However the odor is of little value in preventing excess exposure.

In 2007 the international agency for research on cancer established the association of vcm with hepatocellular carcinoma hcc though only on the basis. How can exposures be reduced. An astheno autonomic syndrome was found in 54 i e. 29 were free of complaints and nervous disturbances.

Most people begin to taste vinyl chloride in water at 3 4 ppm. 27 and in 88 i e. Vinyl chloride is a deadly toxic chemical despite industry s repeated attempts to hide the threats. Vinyl chloride has a mild sweet odor which may become noticeable at 3 000 parts vinyl chloride per million parts ppm of air.

Vinyl chloride is used to make polyvinyl chloride pvc. According to the united states environmental protection agency epa vinyl chloride emissions from polyvinyl chloride pvc ethylene dichloride edc and vinyl chloride monomer vcm plants cause or contribute to air pollution that may reasonably be anticipated to result in an increase in mortality or an increase in serious irreversible or incapacitating reversible illness. Occupational safety health administration provides information about exposure limits to vinyl chloride. Shipped as a liquefied compressed gas.

Chloroethene chloroethylene ethylene monochloride monochloroethene monochloroethylene vc vcm vinyl chloride monomer vcm colorless gas or liquid below 7 f with a pleasant odor at high concentrations. Loss of visual acuity occurs very rapidly and is accompanied by ascending paralysis. The atsdr toxicological profile succinctly characterizes the toxicologic and adverse health effects information for the hazardous substance described here.